82 results
Atmospheric water recycling an essential feature of critical natural asset stewardship
- Patrick W. Keys, Pamela M. Collins, Rebecca Chaplin-Kramer, Lan Wang-Erlandsson
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- Journal:
- Global Sustainability / Volume 7 / 2024
- Published online by Cambridge University Press:
- 23 January 2024, e2
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Non-technical summary
In this paper, we explore how critically important ecosystems on the land provide evaporation to the atmosphere, which will later fall as precipitation elsewhere. Using a model-based analysis that tracks water flowing through the atmosphere, we find that more than two-thirds of the precipitation over critically important ecosystem areas is supplied by evaporation from other land. Likewise, more than 40% of the evaporation from critically important ecosystems falls as precipitation on other land. We conclude our work by discussing the policy implications for how these critically important ecosystems connect spatially distant wild and working lands via the atmospheric water cycle.
Technical summaryGlobal ecosystems are interconnected via atmospheric water vapor flows. Land use change can modify evaporation from land, altering atmospheric moisture recycling and potentially leading to significant changes in downwind precipitation and associated ecological impacts. We combine insights on global ecosystem-regulated moisture recycling with an analysis of critical natural assets (CNA, the 30% of global land providing most of nature's contributions to people) to reveal the sources and sinks of atmospheric water cycle regulation. We find that 65% of the precipitation over CNA is supplied by evaporation from other land areas. Likewise, CNA regions supply critical moisture as precipitation to terrestrial natural ecosystems and production systems worldwide, with 44% of CNA evaporation falling on terrestrial surfaces. Specifically, the Congo River basin emerges as a hotspot of overlap between local atmospheric water cycle maintenance and concentration of nature's contributions to people. Our results suggest global priority areas for conservation efforts beyond and in support of CNA, emphasizing the importance of sparsely populated managed forests and rangelands, along with wild forests, for fostering moisture recycling to and within CNA. This work also underlines the manifold benefits associated with achieving United Nations Sustainable Development Goal #15, to sustainably manage terrestrial life and conserve biodiversity.
Social media summaryCritically important ecosystems are essential for connecting distant landscapes via the atmospheric water cycle.
7 Executive Function is Associated with the Development of Math Performance in Children Born Very Preterm
- Simonne E Collins, Alice C Burnett, Philippa Pyman, Leona Pascoe, Kristina M Haebich, Jeanie L Y Cheong, Lex W Doyle, Deanne K Thompson, Peter J Anderson
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- Journal:
- Journal of the International Neuropsychological Society / Volume 29 / Issue s1 / November 2023
- Published online by Cambridge University Press:
- 21 December 2023, pp. 617-618
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Objective:
To examine associations between executive function (EF) domains (attentional control, information processing, cognitive flexibility, and goal setting) and math computation performance at 7 and 13 years in children born very preterm (VP; <30 weeks' gestation), and secondly, to investigate the associations of 7-year EF with change in math performance from 7 to 13 years.
Participants and Methods:In the prospective, longitudinal Victorian Infant Brain Studies (VIBeS) cohort of children born VP, assessment of EF and math performance was undertaken at 7 (n = 187) and 13 years (n = 174). Univariable and multivariable regression models (including all domains of EF) were used to examine associations between EF domains at both timepoints with math performance, as well as associations between EF at 7 years with change in math from 7 to 13 years.
Results:At 7 and 13 years, all EF domains were positively associated with concurrent math performance, with multivariable models finding information processing, cognitive flexibility and goal setting independently contributed to math performance at both ages. All EF domains were positively associated with improvement in math performance from 7 to 13 years, with multivariable models finding that goal setting contributed unique variance to improvement in math over this period.
Conclusions:This study provides evidence for a strong, consistent association between EF and math performance in children born VP and emphasizes the importance of goal setting capacity for later improvement in math performance.
7 - Comprehensive Evaluation of a Rural School Mental Health Program
- from Part II - Research, Assessment, and Program Evaluation
- Edited by Caroline S. Clauss-Ehlers, Long Island University, New York
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- Book:
- The Cambridge Handbook of Community Psychology
- Published online:
- 16 December 2021
- Print publication:
- 16 December 2021, pp 137-160
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Summary
Promoting youth resilience and well-being in vulnerable rural populations requires a coordinated approach that builds connections between schools, families, community resources, and school mental health clinicians. Emphasizing a community psychology and ecological systems approach, this chapter describes how one school–community–university partnership improved school mental health (SMH) programming and reduced the impacts of adverse childhood experiences (ACEs) in eight rural South Carolina elementary schools. This approach included delivering a continuum of evidence-based SMH services, helping families navigate community resources to address concrete needs that would otherwise function as barriers to student well-being and achievement, building community-level ACE awareness and capacity for resiliency promotion, and conducting a thorough mixed-methods evaluation to highlight program achievements and areas for improvement. Information on the nature and outcomes of the project and strategies for conducting rich evaluations for similar regional programs are presented. Finally, a new model – the Empower Action Model – for organizations interested in developing a functional, coordinated plan of action for improving equity, health, and well-being in their communities is introduced.
Comparing optimized exoskeleton assistance of the hip, knee, and ankle in single and multi-joint configurations
- Patrick W. Franks, Gwendolyn M. Bryan, Russell M. Martin, Ricardo Reyes, Ava C. Lakmazaheri, Steven H. Collins
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- Journal:
- Wearable Technologies / Volume 2 / 2021
- Published online by Cambridge University Press:
- 24 November 2021, e16
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Exoskeletons that assist the hip, knee, and ankle joints have begun to improve human mobility, particularly by reducing the metabolic cost of walking. However, direct comparisons of optimal assistance of these joints, or their combinations, have not yet been possible. Assisting multiple joints may be more beneficial than the sum of individual effects, because muscles often span multiple joints, or less effective, because single-joint assistance can indirectly aid other joints. In this study, we used a hip–knee–ankle exoskeleton emulator paired with human-in-the-loop optimization to find single-joint, two-joint, and whole-leg assistance that maximally reduced the metabolic cost of walking. Hip-only and ankle-only assistance reduced the metabolic cost of walking by 26 and 30% relative to walking in the device unassisted, confirming that both joints are good targets for assistance (N = 3). Knee-only assistance reduced the metabolic cost of walking by 13%, demonstrating that effective knee assistance is possible (N = 3). Two-joint assistance reduced the metabolic cost of walking by between 33 and 42%, with the largest improvements coming from hip-ankle assistance (N = 3). Assisting all three joints reduced the metabolic cost of walking by 50%, showing that at least half of the metabolic energy expended during walking can be saved through exoskeleton assistance (N = 4). Changes in kinematics and muscle activity indicate that single-joint assistance indirectly assisted muscles at other joints, such that the improvement from whole-leg assistance was smaller than the sum of its single-joint parts. Exoskeletons can assist the entire limb for maximum effect, but a single well-chosen joint can be more efficient when considering additional factors such as weight and cost.
Scientific access into Mercer Subglacial Lake: scientific objectives, drilling operations and initial observations
- John C. Priscu, Jonas Kalin, John Winans, Timothy Campbell, Matthew R. Siegfried, Mark Skidmore, John E. Dore, Amy Leventer, David M. Harwood, Dennis Duling, Robert Zook, Justin Burnett, Dar Gibson, Edward Krula, Anatoly Mironov, Jim McManis, Graham Roberts, Brad E. Rosenheim, Brent C. Christner, Kathy Kasic, Helen A. Fricker, W. Berry Lyons, Joel Barker, Mark Bowling, Billy Collins, Christina Davis, Al Gagnon, Christopher Gardner, Chloe Gustafson, Ok-Sun Kim, Wei Li, Alex Michaud, Molly O. Patterson, Martyn Tranter, Ryan Venturelli, Trista Vick-Majors, Cooper Elsworth, The SALSA Science Team
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- Journal:
- Annals of Glaciology / Volume 62 / Issue 85-86 / September 2021
- Published online by Cambridge University Press:
- 08 June 2021, pp. 340-352
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The Subglacial Antarctic Lakes Scientific Access (SALSA) Project accessed Mercer Subglacial Lake using environmentally clean hot-water drilling to examine interactions among ice, water, sediment, rock, microbes and carbon reservoirs within the lake water column and underlying sediments. A ~0.4 m diameter borehole was melted through 1087 m of ice and maintained over ~10 days, allowing observation of ice properties and collection of water and sediment with various tools. Over this period, SALSA collected: 60 L of lake water and 10 L of deep borehole water; microbes >0.2 μm in diameter from in situ filtration of ~100 L of lake water; 10 multicores 0.32–0.49 m long; 1.0 and 1.76 m long gravity cores; three conductivity–temperature–depth profiles of borehole and lake water; five discrete depth current meter measurements in the lake and images of ice, the lake water–ice interface and lake sediments. Temperature and conductivity data showed the hydrodynamic character of water mixing between the borehole and lake after entry. Models simulating melting of the ~6 m thick basal accreted ice layer imply that debris fall-out through the ~15 m water column to the lake sediments from borehole melting had little effect on the stratigraphy of surficial sediment cores.
Effect of selective removal of badgers (Meles meles) on ranging behaviour during a ‘Test and Vaccinate or Remove’ intervention in Northern Ireland
- M. J. H. O'Hagan, A. W. Gordon, C. M. McCormick, S. F. Collins, N. A. Trimble, C. F. McGeown, G. E. McHugh, K. R. McBride, F. D. Menzies
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- Journal:
- Epidemiology & Infection / Volume 149 / 2021
- Published online by Cambridge University Press:
- 07 May 2021, e125
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The role of the Eurasian badger (Meles meles) as a wildlife host has complicated the management of bovine tuberculosis (bTB) in cattle. Badger ranging behaviour has previously been found to be altered by culling of badgers and has been suggested to increase the transmission of bTB either among badgers or between badgers and cattle. In 2014, a five-year bTB intervention research project in a 100 km2 area in Northern Ireland was initiated involving selective removal of dual path platform (DPP) VetTB (immunoassay) test positive badgers and vaccination followed by release of DPP test negative badgers (‘Test and Vaccinate or Remove’). Home range sizes, based on position data obtained from global positioning system collared badgers, were compared between the first year of the project, where no DPP test positive badgers were removed, and follow-up years 2–4 when DPP test positive badgers were removed. A total of 105 individual badgers were followed over 21 200 collar tracking nights. Using multivariable analyses, neither annual nor monthly home ranges differed significantly in size between years, suggesting they were not significantly altered by the bTB intervention that was applied in the study area.
A history of high-power laser research and development in the United Kingdom
- Part of
- Colin N. Danson, Malcolm White, John R. M. Barr, Thomas Bett, Peter Blyth, David Bowley, Ceri Brenner, Robert J. Collins, Neal Croxford, A. E. Bucker Dangor, Laurence Devereux, Peter E. Dyer, Anthony Dymoke-Bradshaw, Christopher B. Edwards, Paul Ewart, Allister I. Ferguson, John M. Girkin, Denis R. Hall, David C. Hanna, Wayne Harris, David I. Hillier, Christopher J. Hooker, Simon M. Hooker, Nicholas Hopps, Janet Hull, David Hunt, Dino A. Jaroszynski, Mark Kempenaars, Helmut Kessler, Sir Peter L. Knight, Steve Knight, Adrian Knowles, Ciaran L. S. Lewis, Ken S. Lipton, Abby Littlechild, John Littlechild, Peter Maggs, Graeme P. A. Malcolm, OBE, Stuart P. D. Mangles, William Martin, Paul McKenna, Richard O. Moore, Clive Morrison, Zulfikar Najmudin, David Neely, Geoff H. C. New, Michael J. Norman, Ted Paine, Anthony W. Parker, Rory R. Penman, Geoff J. Pert, Chris Pietraszewski, Andrew Randewich, Nadeem H. Rizvi, Nigel Seddon, MBE, Zheng-Ming Sheng, David Slater, Roland A. Smith, Christopher Spindloe, Roy Taylor, Gary Thomas, John W. G. Tisch, Justin S. Wark, Colin Webb, S. Mark Wiggins, Dave Willford, Trevor Winstone
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- Journal:
- High Power Laser Science and Engineering / Volume 9 / 2021
- Published online by Cambridge University Press:
- 27 April 2021, e18
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The first demonstration of laser action in ruby was made in 1960 by T. H. Maiman of Hughes Research Laboratories, USA. Many laboratories worldwide began the search for lasers using different materials, operating at different wavelengths. In the UK, academia, industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications. This historical review looks at the contribution the UK has made to the advancement of the technology, the development of systems and components and their exploitation over the last 60 years.
The accuracy of nutrition labels as a means of monitoring the reformulation of food in Ireland - The case of yoghurts
- S. O'Mahony, C. B. O'Donovan, K. McDonald, O. C. Lyons, S. F. Quinn, R. J. Creane, M. A. T. Flynn, W. Anderson, E. R. Gibney, N. A. Collins
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- Journal:
- Proceedings of the Nutrition Society / Volume 79 / Issue OCE2 / 2020
- Published online by Cambridge University Press:
- 10 June 2020, E713
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Over half of the Irish population is overweight or obese. The Obesity Policy and Action Plan 2016–2025 will set reformulation targets for fat, saturated fat and sugar in Ireland and review progress. In 2016, the Food Safety Authority of Ireland undertook a cross-sectional market scan of yoghurts to evaluate the energy, fat, saturated fat and sugar content based solely on declared nutrition labels. The aims of this 2018 study were to verify the accuracy of declared nutrition information on yoghurts and to confirm the suitability of declared nutrition labels for energy, fat, saturated fat and sugar reformulation monitoring.
Yoghurts identified in the 2016 market scan (n578) were weighted based on categorisation of manufacturer type (branded, own brand), product category (natural, flavoured and luxury) and declared nutrition content. Samples (n200) were randomly selected from these weighted groups and tested by a laboratory accredited for energy, fat, saturated fat, and sugar analysis. Data was analysed using IBM SPSS (version25). As data was not normally distributed, median values were investigated for declared and tested energy, fat, saturated fat and sugar content using Wilcoxon Signed-Rank Test and Spearman Rank-Order Correlation.
Of the tested yoghurts, 3% (n6), 5% (n9) and 19% (n31) were outside the recommended European Commission (EC) labelling tolerance for fat, saturated fat and sugar, respectively. Tested nutrient content was consistently lower than declared. There was a statistically significant difference in declared vs. tested energy (87kcal vs. 84kcal p = 0.03), fat (2.7 g vs. 2.5 g p < 0.001), and sugar (9.9 g vs. 8.7 g p < 0.001) content per 100 g yoghurt. Declared vs. tested sugar content per 100 g yoghurt was statistically significant across all yoghurt types, including natural (4.8 g vs. 3.4 g p < 0.001), flavoured (9.7 g vs. 8.6 g p < 0.001) and luxury (15 g vs. 13.6 g p = 0.002). There was a statistically significant difference between declared vs. tested fat (2.8 g vs. 2.5 g p < 0.001) and saturated fat (1.9 g vs.1.6 g p = 0.017) content of own brand yoghurts per 100 g. There was a positive correlation between energy content and portion size (r = .2,p < 0.01).
There was a high level of agreement between declared vs. tested fat and saturated fat content of yoghurts, but a lower level of agreement between declared vs. tested sugar content of yoghurts. This indicates that declared nutrition labels are suitable for reformulation monitoring of fat and saturated fat, but may not be suitable for sugar. This finding will be further investigated and tested in future work planned for nutrition label verification of other food categories.
The use of Nutrition and Health Claims on Yoghurts on the Irish Market
- S. O'Mahony, R.J. Creane, E. Philpott, C. B. O'Donavan, O.C. Lyons, C.M. Donovan, S. F. Quinn, M. A. T. Flynn, W. Anderson, N. A. Collins
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- Journal:
- Proceedings of the Nutrition Society / Volume 79 / Issue OCE2 / 2020
- Published online by Cambridge University Press:
- 10 June 2020, E574
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The use of nutrition and health claims on food is legislated for in Commission Regulation 1924/2006 and SI No. 11 of 2014. This legislation ensures that any claim made on a food label is clear, accurate and substantiated, enabling consumers to make informed choices. A study undertaken by the Food Safety Authority of Ireland (FSAI) in 2009 found that yoghurts were the food category with the highest use of nutrition and health claims on the Irish market.
In 2018, the FSAI undertook a nutrition label verification study to verify the accuracy of declared nutrition information on yoghurts. The aims of this study were to measure the use of nutrition and health claims on a sample of yoghurts available on the Irish market in 2018 and assess their compliance with Regulation 1924/2006 Nutrition and Health Claims made on Food.
Yoghurts identified in a 2016 market scan (n578) were weighted based on categorisation of manufacturer type (branded, own brand), product category (natural, flavoured and luxury) and declared nutrition content. Samples (n200) were randomly selected from these weighted groups for the 2018 nutrition label verification study. A subsample (n100) was randomly sampled and checked for presence of nutrition and health claims. Presence of nutrition and health claims was recorded in Microsoft Excel and checked for compliance with Regulation 1924/2006.
Of the yoghurts reviewed, 67% (n67) made at least one nutrition claim and 34% (n34) made at least one health claim. Of these, 29% (n29) made a nutrition and a health claim. Branded yoghurts were more likely to make nutrition and health claims than own brand yoghurts (78% (n49) vs. 48% (n18)). Of yoghurts with a health claim, 88% (n30) were branded and 12% (n4) were own brand. Of yoghurts with a nutrition claim, 1.5% (n1) made a nutrition claim which was potentially non-compliant with Regulation 1924/2006. Of yoghurts with a health claim, 74% (n23) made a health claim which was potentially non-compliant with Regulation 1924/2006. The majority of potentially non-compliant health claims were in relation to probiotic strains and ‘live cultures’.
In conclusion, yoghurts continue to be a food category which often uses nutrition and health claims. Nutrition and health claims are more frequently used by branded than own brand products. Potentially non-compliant health claims are an issue amongst this food category which will be further investigated and followed up.
Vitamin D deficiency, oxidative stress and antioxidant status: only weak association seen in the absence of advanced age, obesity or pre-existing disease
- Erica W. Wang, Parco M. Siu, Marco Y. Pang, Jean Woo, Andrew R. Collins, Iris F. F. Benzie
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- Journal:
- British Journal of Nutrition / Volume 118 / Issue 1 / 14 July 2017
- Published online by Cambridge University Press:
- 31 July 2017, pp. 11-16
- Print publication:
- 14 July 2017
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Vitamin D deficiency (plasma 25-hydroxycholecalciferol (25(OH)D)<50 nmol/l) is highly prevalent, increases risk of non-communicable diseases (NCD) and associates with increased oxidative stress in obese subjects, the elderly and patients suffering from NCD. If confirmed as an independent driver of oxidative stress, nutritional and other public health strategies to improve vitamin D status would be strongly supported. We investigated vitamin D/oxidative stress links without the confounding effects of advanced age, obesity, smoking or pre-existing disease. Plasma 25(OH)D and biomarkers of oxidative stress and antioxidant status (plasma allantoin, oxidised LDL, ferric reducing antioxidant power (FRAP), ascorbic acid, urine 8-oxo-7,8-dihydro-2'-deoxyguanosine) were measured in fasting samples from 196 consenting, healthy adults aged 18–26 years. Correlation between 25(OH)D and each biomarker as well as biomarker differences across 25(OH)D quartiles and groups (<25/25–49/≥50 nmol/l) were investigated. Median 25(OH)D was 40 nmol/l; >70 % of participants were vitamin D deficient. No significant correlations and no biomarker differences across 25(OH)D quartiles or groups were seen except for total antioxidant status. A weak direct association (r 0·252, P<0·05) was observed between 25(OH)D and FRAP, and those in the lowest 25(OH)D quartile and group had significantly lower FRAP values. Results did not reveal a clear link between vitamin D status and oxidative stress biomarkers in the absence of advanced age, obesity and disease, though some evidence of depleted antioxidant status in those with vitamin D deficiency was seen. Poor antioxidant status may pre-date increased oxidative stress. Study of effects of correction of deficiency on antioxidant status and oxidative stress in vitamin D-deficient but otherwise healthy subjects is needed.
An across-breed genome wide association analysis of susceptibility to paratuberculosis in dairy cattle
- Ahmed M Sallam, Yalda Zare, Fazli Alpay, George E Shook, Michael T Collins, Samir Alsheikh, Mahmoud Sharaby, Brian W Kirkpatrick
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- Journal:
- Journal of Dairy Research / Volume 84 / Issue 1 / February 2017
- Published online by Cambridge University Press:
- 02 March 2017, pp. 61-67
- Print publication:
- February 2017
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Paratuberculosis is a chronic disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). It occurs worldwide and causes a significant loss in the animal production industry. There is no cure for MAP infection and vaccination is problematic. Identification of genetics of susceptibility could be a useful adjunct for programs that focus on management, testing and culling of diseased animals. A case-control, genome-wide association study (GWAS) was conducted using Holstein and Jersey cattle in a combined analysis in order to identify markers and chromosomal regions associated with susceptibility to MAP infection across-breed. A mixed-model method (GRAMMAR-GC) implemented in the GenABEL R package and a Bayes C analysis implemented in GenSel software were used as alternative approaches to conduct GWAS analysis focused on single SNPs and chromosomal segments, respectively. After conducting quality control, 22 406 SNPs from 2157 individuals were available for the GRAMMAR-GC (Bayes C) analysis and 45 640 SNPs from 2199 individuals were available for the Bayes C analysis. One SNP located on BTA27 (8·6 Mb) was identified as moderately associated (P < 5 × 10−5, FDR = 0·44) in the GRAMMAR-GC analysis of the combined breed data. Nine 1 Mb windows located on BTA 2, 3 (3 windows), 6, 8, 25, 27 and 29 each explained ≥1% of the total proportion of genetic variance in the Bayes C analysis. In an analysis ignoring differences in linkage phase, two moderately significantly associated SNPs were identified; ARS-BFGL-NGS-19381 on BTA23 (32 Mb) and Hapmap40994-BTA-46361 on BTA19 (61 Mb). New common genomic regions and candidate genes have been identified from the across-breed analysis that might be involved in the immune response and susceptibility to MAP infection.
Cotton Stage of Growth Determines Sensitivity to 2,4-D
- Seth A. Byrd, Guy D. Collins, A. Stanley Culpepper, Darrin M. Dodds, Keith L. Edmisten, David L. Wright, Gaylon D. Morgan, Paul A. Baumann, Peter A. Dotray, Misha R. Manuchehri, Andrea Jones, Timothy L. Grey, Theodore M. Webster, Jerry W. Davis, Jared R. Whitaker, Phillip M. Roberts, John L. Snider, Wesley M. Porter
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- Journal:
- Weed Technology / Volume 30 / Issue 3 / September 2016
- Published online by Cambridge University Press:
- 20 January 2017, pp. 601-610
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The anticipated release of EnlistTM cotton, corn, and soybean cultivars likely will increase the use of 2,4-D, raising concerns over potential injury to susceptible cotton. An experiment was conducted at 12 locations over 2013 and 2014 to determine the impact of 2,4-D at rates simulating drift (2 g ae ha−1) and tank contamination (40 g ae ha−1) on cotton during six different growth stages. Growth stages at application included four leaf (4-lf), nine leaf (9-lf), first bloom (FB), FB + 2 wk, FB + 4 wk, and FB + 6 wk. Locations were grouped according to percent yield loss compared to the nontreated check (NTC), with group I having the least yield loss and group III having the most. Epinasty from 2,4-D was more pronounced with applications during vegetative growth stages. Importantly, yield loss did not correlate with visual symptomology, but more closely followed effects on boll number. The contamination rate at 9-lf, FB, or FB + 2 wk had the greatest effect across locations, reducing the number of bolls per plant when compared to the NTC, with no effect when applied at FB + 4 wk or later. A reduction of boll number was not detectable with the drift rate except in group III when applied at the FB stage. Yield was influenced by 2,4-D rate and stage of cotton growth. Over all locations, loss in yield of greater than 20% occurred at 5 of 12 locations when the drift rate was applied between 4-lf and FB + 2 wk (highest impact at FB). For the contamination rate, yield loss was observed at all 12 locations; averaged over these locations yield loss ranged from 7 to 66% across all growth stages. Results suggest the greatest yield impact from 2,4-D occurs between 9-lf and FB + 2 wk, and the level of impact is influenced by 2,4-D rate, crop growth stage, and environmental conditions.
Origins and antiquity of the island fox (Urocyon littoralis) on California's Channel Islands
- Torben C. Rick, Jon M. Erlandson, René L. Vellanoweth, Todd J. Braje, Paul W. Collins, Daniel A. Guthrie, Thomas W. Stafford, Jr.
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- Journal:
- Quaternary Research / Volume 71 / Issue 2 / March 2009
- Published online by Cambridge University Press:
- 20 January 2017, pp. 93-98
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The island fox (Urocyon littoralis) is one of few reportedly endemic terrestrial mammals on California's Channel Islands. Questions remain about how and when foxes first colonized the islands, with researchers speculating on a natural, human-assisted, or combined dispersal during the late Pleistocene and/or Holocene. A natural dispersal of foxes to the northern Channel Islands has been supported by reports of a few fox bones from late Pleistocene paleontological localities. Direct AMS 14C dating of these “fossil” fox bones produced dates ranging from ∼ 6400 to 200 cal yr BP, however, postdating human colonization of the islands by several millennia. Although one of these specimens is the earliest securely dated fox from the islands, these new data support the hypothesis that Native Americans introduced foxes to all the Channel Islands in the early to middle Holocene. However, a natural dispersal for the original island colonization cannot be ruled out until further paleontological, archaeological, and genetic studies (especially aDNA [ancient DNA]) are conducted.
Holographic techniques for whole-field thermal and fluid measurements*
- M. W. Collins
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- The Aeronautical Journal / Volume 95 / Issue 949 / November 1991
- Published online by Cambridge University Press:
- 04 July 2016, pp. 313-323
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Measurement methods using holography are non-invasive, whole-field and can be applied in real-time. They are particularly appropriate for experimental validation of current CFD (computational fluid dynamics) codes which have 3-dimensional, transient, irregular geometry capabilities.
In holographic interferometry, the fringes formed by refractive index changes represent lines of constant Mach number in isentropic compressible flows and isotherms in convection. Examples are given of two-dimensional inter-ferograms in these areas, and their quantitative interpretation.
Automatic fringe and data processing is a necessity, and the method is extendable to three dimensions using tomographical reconstruction. These issues are discussed, together with the general question of comparison with flow predictions.
Fluid fields may also be treated on a three-dimensional time-dependent basis, using HCV (holocinematographic velocimetry), a holographic extension of PIV (particle image velocimetry). It is proposeds to run an experiment to measure both fluid and thermal fields, and surface temperatures simultaneously, using HCV or PIV, holographic interferometry and liquid crystal methods respectively.
The establishment of DOHaD working groups in Australia and New Zealand
- Part of
- S. L. Prescott, K. Allen, K. Armstrong, C. Collins, H. Dickinson, K. Gardiner, F. Jacka, C. Jasoni, T. Moore, K. M. Moritz, B. Muhlhausler, W. Siero, K. Sim, R. Nanan, R. Saffery, G. Singh, M. H Vickers, J. M. Craig
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- Journal:
- Journal of Developmental Origins of Health and Disease / Volume 7 / Issue 5 / October 2016
- Published online by Cambridge University Press:
- 27 April 2016, pp. 433-439
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The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and replication. DOHaD meetings are facilitating this interaction. However, strategies to perpetuate focussed discussions and collaborations around and between conferences are more likely to facilitate the development of DOHaD research. For this reason, the DOHaD Society of Australia and New Zealand (DOHaD ANZ) has initiated themed Working Groups, which convened at the 2014–2015 conferences. This report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities. One of the first Working Groups to form was the ActEarly birth cohort group, which is moving towards more translational goals. Reflecting growing emphasis on the impact of early life biodiversity – even before birth – we also have a Working Group titled Infection, inflammation and the microbiome. We have several Working Groups exploring other major non-cancerous disease outcomes over the lifespan, including Brain, behaviour and development and Obesity, cardiovascular and metabolic health. The Epigenetics and Animal Models Working Groups cut across all these areas and seeks to ensure interaction between researchers. Finally, we have a group focussed on ‘Translation, policy and communication’ which focusses on how we can best take the evidence we produce into the community to effect change. By coordinating and perpetuating DOHaD discussions in this way we aim to enhance DOHaD research in our region.
Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial
- J. W. Murrough, L. Soleimani, K. E. DeWilde, K. A. Collins, K. A. Lapidus, B. M. Iacoviello, M. Lener, M. Kautz, J. Kim, J. B. Stern, R. B. Price, A. M. Perez, J. W. Brallier, G. J. Rodriguez, W. K. Goodman, D. V. Iosifescu, D. S. Charney
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- Journal:
- Psychological Medicine / Volume 45 / Issue 16 / December 2015
- Published online by Cambridge University Press:
- 12 August 2015, pp. 3571-3580
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Background.
Suicide is a devastating public health problem and very few biological treatments have been found to be effective for quickly reducing the intensity of suicidal ideation (SI). We have previously shown that a single dose of ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, is associated with a rapid reduction in depressive symptom severity and SI in patients with treatment-resistant depression.
Method.We conducted a randomized, controlled trial of ketamine in patients with mood and anxiety spectrum disorders who presented with clinically significant SI (n = 24). Patients received a single infusion of ketamine or midazolam (as an active placebo) in addition to standard of care. SI measured using the Beck Scale for Suicidal Ideation (BSI) 24 h post-treatment represented the primary outcome. Secondary outcomes included the Montgomery–Asberg Depression Rating Scale – Suicidal Ideation (MADRS-SI) score at 24 h and additional measures beyond the 24-h time-point.
Results.The intervention was well tolerated and no dropouts occurred during the primary 7-day assessment period. BSI score was not different between the treatment groups at 24 h (p = 0.32); however, a significant difference emerged at 48 h (p = 0.047). MADRS-SI score was lower in the ketamine group compared to midazolam group at 24 h (p = 0.05). The treatment effect was no longer significant at the end of the 7-day assessment period.
Conclusions.The current findings provide initial support for the safety and tolerability of ketamine as an intervention for SI in patients who are at elevated risk for suicidal behavior. Larger, well-powered studies are warranted.
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. 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- Edited by Robert Audi, University of Notre Dame, Indiana
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- The Cambridge Dictionary of Philosophy
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- 05 August 2015
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- 27 April 2015, pp ix-xxx
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- By Dor Abrahamson, Jerry Andriessen, Roger Azevedo, Michael Baker, Ryan Baker, Sasha Barab, Carl Bereiter, Susan Bridges, Mario Carretero, Carol K. K. Chan, Clark A. Chinn, Paul Cobb, Allan Collins, Kevin Crowley, Elizabeth A. Davis, Chris Dede, Sharon J. Derry, Andrea A. diSessa, Michael Eisenberg, Yrjö Engeström, Noel Enyedy, Barry J. Fishman, Ricki Goldman, James G. Greeno, Erica Rosenfeld Halverson, Cindy E. Hmelo-Silver, Michael J. Jacobson, Sanna Järvelä, Yasmin B. Kafai, Yael Kali, Manu Kapur, Paul A. Kirschner, Karen Knutson, Timothy Koschmann, Joseph S. Krajcik, Carol D. Lee, Peter Lee, Robb Lindgren, Jingyan Lu, Richard E. Mayer, Naomi Miyake, Na’ilah Suad Nasir, Mitchell J. Nathan, Narcis Pares, Roy Pea, James W. Pellegrino, William R. Penuel, Palmyre Pierroux, Brian J. Reiser, K. Ann Renninger, Ann S. Rosebery, R. Keith Sawyer, Marlene Scardamalia, Anna Sfard, Mike Sharples, Kimberly M. Sheridan, Bruce L. Sherin, Namsoo Shin, George Siemens, Peter Smagorinsky, Nancy Butler Songer, James P. Spillane, Kurt Squire, Gerry Stahl, Constance Steinkuehler, Reed Stevens, Daniel Suthers, Iris Tabak, Beth Warren, Uri Wilensky, Philip H. Winne, Carmen Zahn
- Edited by R. Keith Sawyer, University of North Carolina, Chapel Hill
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- The Cambridge Handbook of the Learning Sciences
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- 05 November 2014
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- By Michael H. Allen, Leora Amira, Victoria Arango, David W. Ayer, Helene Bach, Christopher R. Bailey, Ross J. Baldessarini, Kelsey Ball, Alan L. Berman, Marian E. Betz, Emily A. Biggs, R. Warwick Blood, Kathleen T. Brady, David A. Brent, Jeffrey A. Bridge, Gregory K. Brown, Anat Brunstein Klomek, A. Jacqueline Buchanan, Michelle J. Chandley, Tim Coffey, Jessica Coker, Yeates Conwell, Scott J. Crow, Collin L. Davidson, Yogesh Dwivedi, Stacey Espaillat, Jan Fawcett, Steven J. Garlow, Robert D. Gibbons, Catherine R. Glenn, Deborah Goebert, Erica Goldstein, Tina R. Goldstein, Madelyn S. Gould, Kelly L. Green, Alison M. Greene, Philip D. Harvey, Robert M. A. Hirschfeld, Donna Holland Barnes, Andres M. Kanner, Gary J. Kennedy, Stephen H. Koslow, Benoit Labonté, Alison M. Lake, William B. Lawson, Steve Leifman, Adam Lesser, Timothy W. Lineberry, Amanda L. McMillan, Herbert Y. Meltzer, Michael Craig Miller, Michael J. Miller, James A. Naifeh, Katharine J. Nelson, Charles B. Nemeroff, Alexander Neumeister, Matthew K. Nock, Jennifer H. Olson-Madden, Gregory A. Ordway, Michael W. Otto, Ghanshyam N. Pandey, Giampaolo Perna, Jane Pirkis, Kelly Posner, Anne Rohs, Pedro Ruiz, Molly Ryan, Alan F. Schatzberg, S. Charles Schulz, M. Katherine Shear, Morton M. Silverman, April R. Smith, Marcus Sokolowski, Barbara Stanley, Zachary N. Stowe, Sarah A. Struthers, Leonardo Tondo, Gustavo Turecki, Robert J. Ursano, Kimberly Van Orden, Anne C. Ward, Danuta Wasserman, Jerzy Wasserman, Melinda K. Westlund, Tracy K. Witte, Kseniya Yershova, Alexandra Zagoloff, Sidney Zisook
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- A Concise Guide to Understanding Suicide
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- 05 October 2014
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Impulsivity in disorders of food and drug misuse
- T. B. Mole, M. A. Irvine, Y. Worbe, P. Collins, S. P. Mitchell, S. Bolton, N. A. Harrison, T. W. Robbins, V. Voon
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- Psychological Medicine / Volume 45 / Issue 4 / March 2015
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- 14 August 2014, pp. 771-782
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Background.
Evidence suggests some overlap between the pathological use of food and drugs, yet how impulsivity compares across these different clinical disorders remains unclear. Substance use disorders are commonly characterized by elevated impulsivity, and impulsivity subtypes may show commonalities and differences in various conditions. We hypothesized that obese subjects with binge-eating disorder (BED) and abstinent alcohol-dependent cohorts would have relatively more impulsive profiles compared to obese subjects without BED. We also predicted decision impulsivity impairment in obesity with and without BED.
Method.Thirty obese subjects with BED, 30 without BED and 30 abstinent alcohol-dependent subjects and age- and gender-matched controls were tested on delay discounting (preference for a smaller immediate reward over a larger delayed reward), reflection impulsivity (rapid decision making prior to evidence accumulation) and motor response inhibition (action cancellation of a prepotent response).
Results.All three groups had greater delay discounting relative to healthy volunteers. Both obese subjects without BED and alcohol-dependent subjects had impaired motor response inhibition. Only obese subjects without BED had impaired integration of available information to optimize outcomes over later trials with a cost condition.
Conclusions.Delay discounting appears to be a common core impairment across disorders of food and drug intake. Unexpectedly, obese subjects without BED showed greater impulsivity than obese subjects with BED. We highlight the dissociability and heterogeneity of impulsivity subtypes and add to the understanding of neurocognitive profiles across disorders involving food and drugs. Our results have therapeutic implications suggesting that disorder-specific patterns of impulsivity could be targeted.